human immunodeficiency virus — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TN2283	Tripterifordin		HIV Protease
	Tripterifordin shows anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 1 microgram/ml.		HIV Protease
T6377	Aloperine		Apoptosis , Virus Protease , HIV Protease , Antibiotic , Autophagy
	Aloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.
TP1809	TAT		HIV Protease
	TAT peptide (YGRKKRRQRRR), originating from the human immunodeficiency virus-1 (HIV-1) transactivator of transcription (TAT), enhances the solubility and production of heterologous proteins[1]. This cell-penetrating pept...		HIV Protease
T38514	PMEDAP		Others , HIV Protease
	PMEDAP is a potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and associated mortality and an inhibitor of human immunodeficiency virus (HIV) replication. PMEDAP also has anti-murine cytomega...		Others , HIV Protease
T12953	Sodium copper chlorophyllin B		Influenza Virus , HIV Protease
	Sodium copper chlorophyllin B exerts antiviral activities against Influenza virus and HIV.		Influenza Virus , HIV Protease
T16764	RN-18		HIV Protease
	RN-18 is an inhibitor of HIV-1 viral infectivity factor (IC50: 6 μM in nonpermissive H9 cells).		HIV Protease
T10111	3-Deazaadenosine hydrochloride		Others , HIV Protease
	3-Deazaadenosine hydrochloride is an inhibitor of S-adenosylhomocysteine hydrolase (Ki: 3.9 µM). It has anti-inflammatory, anti-proliferative, and anti-HIV activity.		Others , HIV Protease
T12715	Reverse transcriptase-IN-1		HIV Protease
	Reverse transcriptase-IN-1 is a diarylbenzopyrimidine (DABP) analogue and a potent inhibitor of HIV-1 nonnucleoside reverse transcriptase with an IC50of 13.7 nM.		HIV Protease
T15436	GSK2838232		HIV Protease
	GSK2838232 inhibit HIV reverse transcriptase activity across a broad panel of HIV-1 isolates,GSK2838232 is novel human immune virus (HIV) maturation inhibitor.		HIV Protease
T9063	Clathrin-IN-1		HIV Protease
	Clathrin-IN-1 is a inhibitor of clathrin, and inhibits clathrin-mediated endocytosis (CME) by associating with the terminal domain of clathrin. It has the potential for anti-cancer research.		HIV Protease
T2942	Psoralen	Ficusin,Furocoumarin,psoralene	Apoptosis , Influenza Virus , HIV Protease , DNA/RNA Synthesis
	Psoralen (Ficusin) is a furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division.
T16276	NBD-556		HIV Protease
	NBD-556 is a small molecule mimetic of CD4. NBD-556 recognizes the HIV-1 envelope protein gp120 and induces restructuring of gp120 analogous to CD4 binding.		HIV Protease
TQ0217	Gomisin G		P450 , HIV Protease
	Gomisin G is a natural compound and exhibits potent anti-HIV activity (EC50: 0.006 μg/mL; therapeutic index: 300). It is a good substrate of CYP2C9.		P450 , HIV Protease
T6256	YYA-021	YYA 021	gp120/CD4 , HIV Protease
	YYA-021 inhibits HIV entry, with high anti-HIV activity and low cytotoxicity.		gp120/CD4 , HIV Protease
TN1103	Diphyllin		ATPase , Proton pump , Influenza Virus , HIV Protease
	Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.		ATPase , Proton pump , Influenza Virus , HIV Protease
T4665	Temsavir	BMS626529	HIV Protease
	Temsavir (BMS626529) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.		HIV Protease
T15210	Elsulfavirine	Elpida,VM-1500	HIV Protease
	Elsulfavirine (VM-1500) is an HIV-1 infection reverse transcriptase inhibitor. It is a new anti-HIV drug.		HIV Protease
T0836	Sulfadoxine	Sulphadoxine	DHFR , HIV Protease , Antibiotic , Parasite , Autophagy
	Sulfadoxine (Sulphadoxine) is a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with bacteriostatic and antimalarial properties.		DHFR , HIV Protease , Antibiotic , Parasite , Autophagy
T0457	Probenecid	Benemid	HIV Protease , Antibacterial , TRP/TRPV Channel
	Probenecid (Benemid) is a benzoic acid derivative with antihyperuricemic property.		HIV Protease , Antibacterial , TRP/TRPV Channel
T8311	Obefazimod	ABX-464,ABX464	HIV Protease
	Obefazimod (ABX-464) is a potent anti-HIV agent. ABX464 inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs) (IC50 : 0.1 μM - 0.5 μM)		HIV Protease